The Role of SLC24A5 in Zebrafish and Human Pigmentation

Figure 1. Phenotype of golden zebrafish.

Figure 1. Phenotype of golden zebrafish. Lateral views of adult wild-type (A) and golden (B) zebrafish. Insets show melanophores (arrowheads). Scale bars, 5 mm (inset, 0.5 mm). golb1 mutants have melanophores that are, on average, smaller, more pale, and transparent. Transmission electron micrographs of skin melanophore from 55-hpf wild-type (C and E) and golb1 (D and F) larvae. golb1 skin melanophores (arrowheads show edges) are thinner and contain fewer melanosomes than do those of wild type. Melanosomes of golb1 larvae are fewer in number, smaller, less-pigmented, and irregular compared with wild type.

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