Puberty Initiation in Mammals: Colocalization of NKB and Kisspeptin

figure 8

Figure 8: From previous study, corresponding dose of Kp-10 that induces a physiological discharge of LH was 2 µg (26). 2 µg of Kp-10 produced a LH discharge with amplitude greater than that observed in 50 µg senktide response (figure3). If clearance of injected Kp-10 and senktide from the circulation is similar and distribution to the hypothalamus is comparable, then it would be concluded that Kp-10 is the most potent releaser of GnRH.

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