This is a working, or draft schedule of topics for Spring 2015. The schedule may be adjusted during the semester. The research papers for discussion are also subject to change.
Date | Topic | Resources |
5-Jan | Questions of developmental biology; model organisms |
|
7-Jan | Sporulation in B. subtilis | |
9-Jan | B. subtilis sporulation | Camp et al. 2011 |
12-Jan | B. subtilis sporulation | Camp et al. 2011 |
14-Jan | Yeast mating type differentiation | http://www.devbio.biology.gatech.edu/?page_id=30 |
16-Jan | Asymmetric cell division in yeast | http://www.wikigenes.org/e/gene/e/853650.html |
19-Jan | MLK Holiday | |
21-Jan | Asymmetric cell division in yeast | Niedner et al. 2013 |
23-Jan | Dictyostelium discoideum | http://www.devbio.biology.gatech.edu/?page_id=34 |
26-Jan | Dictyostelium discoideum | abstract & introduction of Saito et al. 2008 |
28-Jan | Dictyostelium slug patterning; take-home quiz 1 posted | Chen & Schaap 2012 |
30-Jan | Quiz 1 in-class group discussion |
Chen & Schaap 2012 |
2-Feb | C. elegans maternal effect mutations & cytoplasmic determinants | |
4-Feb | A-P patterning in C. elegans | Motegi et al. 2011 |
6-Feb | Endoderm specification in C. elegans | |
9-Feb | Drosophila gametogenesis and embryogenesis | http://www.devbio.biology.gatech.edu/?page_id=44 |
11-Feb | Drosophila maternal genes | Frohnhofer et al. 1985; Nusslein-Volhard et al. 1987 |
13-Feb | Drosophila A-P axis determination | Eric Wieschaus video |
16-Feb | Drosophila dorso-ventral axis patterning | Kugler & Lasko 2009 |
18-Feb | Drosophila paper discussion | Cho et al. 2012 |
20-Feb | homeo box genes | Lemons & McGinnis 2006 |
23-Feb | Sea urchins & deuterostomes – fertilization | http://www.devbio.biology.gatech.edu/?page_id=396 |
25-Feb | Midterm 2 | Take-home quiz 2 in-class discussion |
27-Feb | Cleavage and gastrulation | |
2-Mar | amphibians axis formation | http://www.devbio.biology.gatech.edu/?page_id=49 |
4-Mar | Spemann’s organizer and comparative vertebrate embryology | http://scienceblogs.com/pharyngula/2006/07/17/the-evolution-of-deuterostome/ |
6-Mar | mesoderm induction | Birsoy et al. 2006 |
9-Mar | Zebrafish development (1) Early endoderm development) | Ober et al., 2003 |
11-Mar | Zebrafish development (2) Liver and pancreas development | |
13-Mar | Zebrafish development (3) Transgenic techniques | Suster et al., 2009 |
16-20 Mar | Spring Break | |
23-Mar | Mouse development (1) Heart development | Olson, 2006 |
25-Mar | Mouse development (2) Fate decision | Wandzioch and Zaret, 2009 |
27-Mar | Mouse development (3) Epigenetics | |
30-Mar | Stem cells (1) Induced pluripotent stem cells | Takahashi and Yamanaka, 2006 |
1-Apr | Stem cells (2) Embryonic stem cells | Pagliuca et al., 2014 |
3-Apr | In-class exam | |
6-Apr | Stem cells (3) Neural stem cells | Lavado et al., 2013 |
8-Apr | Stem cells (4) Hematopoietic stem cells | Martin et al., 2011 |
10-Apr | Peer review practice | |
13-Apr | Stem cells (5) Reprogramming | |
15-Apr | Regeneration (1) Heart I | |
17-Apr | Regeneration (2) Heart II | Zhang et al., 2013 |
20-Apr | Regeneration (3) Liver | Huang et al., 2014 |
22-Apr | Regeneration (4) Insulin secreting beta cells | Andersson et al., 2012 |
24-Apr | Course review and wrap-up | |
27-Apr | Final exam on last 1/4 of course | 11:30 – 2:20 |